Lormeg tablets

Lormeg

  • Active Ingredient: Loratadine
  • 10 mg
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What is Lormeg?

The active ingredient of Lormeg brand is loratadine. Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Used for

Lormeg is used to treat diseases such as: Allergic Reactions, Allergic Rhinitis, Urticaria.

Side Effect

Possible side effects of Lormeg include: ; ; ; ; ; ; .

How to Buy Lormeg tablets online?

To purchase Lormeg online - just click on the "Buy Now" button in the top and follow along with our shop. Payment and Order takes a couple of minutes, and all measures are obvious. We do not take a medical prescription plus also we have many methods of payment. With all the details of rapid shipping and confidentiality, you may read on the relevant pages on the hyperlinks from the top menu.

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What other drugs will affect Lormeg?

Other drugs may interact with Lormeg, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What are cetirizine and Lormeg?

Cetirizine is a non-sedating antihistamine. It is similar to other second-generation antihistamines including Lormeg (Claritin), fexofenadine (Allegra) and azelastine (Astelin). Histamine is a chemical responsible for many of the signs and symptoms of allergic reactions such as swelling of the lining of the nose, sneezing, and itchy eyes. Certirizine blocks one type of receptor for histamine (the H1 receptor) and prevents activation of H1 receptor-containing cells by histamine. Unlike first generation antihistamines, cetirizine and other second-generation antihistamines do not readily enter the brain from the blood so they cause less drowsiness though cetirizine may cause more drowsiness than other second-generation antihistamines.

Lormeg is a long-acting, non-sedating antihistamine used to treat allergies. Lormeg blocks one type of histamine receptor (the H1 receptor) and thus prevents activation of cells with H1 receptors by histamine. Unlike some antihistamines, Lormeg does not enter the brain from the blood and does not cause drowsiness when taken at recommended doses.

4. How and when to take it

If you or your child have been prescribed Lormeg, follow your doctor's instructions about how and when to take it. If you've bought Lormeg from a pharmacy or shop, follow the instructions that come with the packet.

When to take it

You may only need to take Lormeg on a day you have symptoms, for instance if you've been exposed to a trigger such as animal hair. Or you may need to take it regularly to prevent symptoms, such as hay fever during spring and summer.

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Anti-histamines

Histamine mediates most of its effects on airway function via H1-receptors. Non-sedating potent H1 -receptor antagonists, such as terfenadine, fexafenadine, Lormeg , desLormeg, ebastine, and astemizole, have useful clinical effects in allergic rhinitis, but they are far from effective in asthmatic patients . The effects of anti-histamines are small and clinically insignificant. Terfenadine causes about 50% inhibition of the immediate response to allergen, but has no effect on the late response . Anti-histamines cause a small degree of bronchodilatation in asthmatic patients, indicating a certain degree of histamine “tone,” presumably due to the basal release of histamine from activated mast cells . Chronic administration of terfenadine has a small clinical effect in mild allergic asthmatic patients, but is far less effective that other anti-asthma therapies. H1-receptor antagonists have not been found to be useful in more severe asthmatic patients . The new generation anti-histamines, cetirizine and astemizole, have some beneficial effects in asthma, that may be unrelated to their H1-antagonist effects .

H2-antagonists, such as cimetidine and ranitidine, may be contraindicated in asthma on theoretical grounds, if H2-receptors are important in counteracting the bronchoconstrictor effect of histamine. In clinical practice, however, there is no evidence that H2-antagonists have any deleterious effect in asthma. H3-receptor agonists may have some theoretical benefit in asthma, since they may modulate cholinergic bronchoconstriction and inhibit neurogenic inflammation. Although (R)-α-methylhistamine relaxes rodent peripheral airways in vitro, it has no effect when given by inhalation on airway caliber or metabisufite-induced bronchoconstriction in asthmatic patients, indicating that a useful clinical effect is unlikely .

Histamine H4-receptors are expressed on eosinophils, T- cells, dendritic cells, basophils and mast cells, mediate mast cell, eosinophil and dendritic cell chemotaxis, and modulate cytokine production from dendritic cells and T-cells, indicating that blockade of histamine H4-receptors may lead to anti-allergic and anti-inflammatory effects. Several histamine H4-receptor antagonists are now available but remain to be tested in allergic asthma or rhinitis . Antagonists that block both histamine H1- and H4-receptors may be an effective combination. Anti-histamines have a useful effect in the treatment of rhinitis, and particularly the rhinorrhea. As a large proportion of patients with asthma have concomitant rhinitis, an H1-antagonist may help the overall management of asthma . While H1-receptor antagonists alone may be ineffective, some studies suggest that they may have some efficacy in combination with other antagonists. Thus, an H1-receptor antagonist when added to an anti-leukotriene was able to inhibit the early and late responses to allergen more effectively than the anti-leukotriene alone , but as yet there has been no studies of combination mediator antagonists in asthma.

There is no evidence that anti-histamines have any role in the treatment of COPD.

What is the difference between cetirizine and Lormeg?

  • Cetirizine and Lormeg are non-sedating antihistamines used to treat symptoms of allergic reaction such as symptoms of seasonal hay fever (allergic rhinitis) such as sneezing, runny nose, red/watery/itchy eyes, hives, and allergic skin rash.
  • Brand names for Cetirizine include Zyrtec, Zyrtec Allergy, and Zyrtec Hives Relief. Brand names for Lormeg include Claritin, Claritin RediTabs, Alavert, Claritin Hives Relief, Children's Claritin, and others.
  • Both cetirizine and Lormeg are available over-the-counter (OTC) and in generic form.
  • Side effects of cetirizine and Lormeg that are similar include drowsiness, dry mouth, headache, and fatigue.
  • Side effects of cetirizine that are different from Lormeg include nausea, jitteriness, and sore throat.
  • Side effects of Lormeg that are different from cetirizine include nervousness and difficulty sleeping.

Lormeg (SED-14, 488; SEDA-22, 178; SEDA-26, 182; SEDA-27, 169)

Lormeg caused a fixed drug reaction in an 8-year-old boy with perennial rhinitis, asthma, and marked hypersensitivity to house-dust mites. The reaction produced a well-defined erythematous and edematous plaque in his right elbow. The rash resolved without treatment in 1 week (54 A ).


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